In vitro fertilization embryo transfer (commonly known as the first generation): It varies from person to person. After using different plans of ovulation induction drugs, when the eggs mature, the eggs are removed through the vagina under the guidance of B-ultrasound and the husband's semen (processed) They are fertilized in a petri dish and developed into embryos, which are then placed in the woman's uterus. The total cost of surgery and medicine is about 15,000 yuan.

In vitro microinsemination and embryo transfer technology (commonly known as the second generation) is suitable for patients with extremely oligospermic and asthenozoospermic conditions. If in vitro fertilization cannot be achieved using the above methods (commonly known as the first generation), microinjection technology can be used to inject sperm into the egg. Helps fertilization within the cytoplasm of mother cells. For men who have no sperm, they can collect sperm through epididymal aspiration or testicular biopsy technology, and use microscopy technology to obtain their own children. Do not blindly accept sperm donations from others, but the man must first take blood to check whether there are any abnormalities in the chromosomal model to avoid inheritance. The disease is passed on to future generations. Even so, some small gene deletions still cannot be detected. Therefore, while microinjection technology is used to assist pregnancy, there is a possibility that the offspring will have genetic diseases. The total cost of surgery and medicine is about 18,000 yuan to 20,000 yuan. The success rate of this technology is 45%-50%.

Embryo screening to prevent genetic diseases (commonly known as the third generation) screens the embryos developed by couples with genetic diseases through in vitro fertilization, and transplants embryos without genetic disease genes into the woman's uterus. The cost of surgery and medicine for this technology is about 20,000 yuan to 30,000 yuan.

Frozen storage of embryos: If multiple eggs are obtained from one stimulation cycle and fertilized and split in vitro to form multiple embryos, the remaining embryos of good quality after transplantation can be frozen and stored. If pregnancy does not occur during this cycle, the transplant can be thawed in a subsequent natural cycle. The endocrine environment of the natural cycle is conducive to embryo implantation, but freezing and thawing will cause damage to the embryo, and its vitality will be worse than that of fresh embryos.

Egg donation in vitro fertilization: A small number of patients whose ovaries are unable to produce eggs due to genetic factors or premature menopause can borrow other people's eggs, inseminate them with their husband's sperm in vitro, and transplant the embryos into the patient's uterus. The egg donor should be young and have given birth to children. The patient should find a sister or friend to donate eggs, but both parties must sign and agree. Before entering the treatment cycle, contraceptive pills or artificial cycle adjustment drugs should be used to synchronize the menstrual cycles of the egg donor and the egg donor. Patients with amenorrhea should undergo artificial cycles for several months in advance and confirm that the endometrium is suitable for embryo implantation.

Surrogate mother: Some patients have had their uterus removed due to illness but still retain their ovaries or for other reasons such as intrauterine adhesions. They urgently want to have their own children. They can use "test tube baby" technology to transplant early embryos into the uterus of other women. , surrogate conception and birth, the child born genetically belongs to both spouses. The difficulty is that finding a surrogate mother must comply with the family planning policy in my country, and both the couple must sign and agree to the surrogate mother approved by the relevant family planning department. In order for the surrogate mother to receive the embryo, the menstrual cycles of the two people need to be adjusted and synchronized.

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