Premature ejaculation, impotence and other diseases have brought great pain to men, affected the normal sexual life between couples, and also caused great damage to men's self-esteem. It can be said that they have brought great harm to male friends. The gospel saves male friends in trouble. * is a prescription drug, and there are many precautions when taking *. The following editor will introduce to you the three types of drugs that cannot be taken with *.

There are currently three most common prescription drugs used to treat impotence, namely *, Cialis, and Levitra. They all belong to the class of 5-phosphodiesterase inhibitors and are particularly widely used in elderly men. Since the above-mentioned patients often take other drugs at the same time, there may be interactions between these drugs and anti-ED drugs. Male friends, especially elderly male friends, must not take this lightly.

Male impotence medicines cannot be used together with the following three medicines

1. Cannot be used together with dexamethasone

Experts say that carbamazepine, dexamethasone, and rifampicin are drugs that enhance the activity of CYP3A4 and can reduce the effect of anti-ED drugs. Of course, this is not dangerous, but it will make anti-ED drugs ineffective. If CYP3A4 activity is significantly enhanced, as in patients taking rifampicin, even the highest recommended doses of anti-ED drugs will be ineffective.

2. Do not use it together with ketoconazole

Ketoconazole is a common antifungal drug. Patients taking anti-ED drugs and ketoconazole at the same time may increase the chance of adverse reactions to anti-ED drugs. Drugs that work in the same way include clarithromycin, cyclosporine, itraconazole, and ritonavir.

The human body cannot metabolize drugs without the help of enzymes, and CYP3A4 is the most important enzyme in drug metabolism. Most drugs, including anti-ED drugs, are metabolized by CYP3A4, and the above-mentioned drugs can inhibit the activity of CYP3A4. Taking them at the same time as anti-ED drugs may increase the concentration of the former in the blood and increase the potential toxicity of the drug. It is not just drugs that have this effect. Certain drinks, such as grapefruit juice, can also inhibit the activity of CYP3A4. Patients taking anti-ED drugs must stay away from them.

3. Do not use it together with nitroglycerin

Need to take nitrate drugs (such as nitroglycerin) or alpha-blockers (such as doxazosin, prazosin, terazosin, tamsulosin, and alfuzosin, etc.) Patients need to use anti-ED drugs with caution.

This is because *, Cialis, and Levitra all have the effect of dilating blood vessels, and nitroglycerin and prazosin also have the effect of dilating blood vessels. When used in combination, this effect will be amplified, significantly lowering blood pressure and increasing the risk of heart disease. risk of illness or stroke. If you are currently taking such antihypertensive drugs, please consult your physician before taking anti-ED drugs. He may be able to advise you to adjust the dosage.

Revealing 5 Wrong Ways to Aphrodisiac

Oysters are an aphrodisiac delicacy advocated by Europeans and Americans. Surveys show that 25% of people think they have aphrodisiac effects. Joy Davidson, a psychologist and author of "Fearless Sex," believes that the special shape of oysters, often compared to female genitalia, may stimulate male sexual desire from a psychological perspective. But from a nutritional perspective, oysters contain a large amount of minerals and the trace element zinc, which can only help improve system immunity, but it is absolutely impossible to increase sexual desire.

2. Chocolate aphrodisiac

Maybe it’s because of Valentine’s Day, people are used to associate chocolate with love. However, in the research of psychologist and sexual health expert Linda Davidler, the main component of chocolate is cocoa, which can resist oxidation and lower blood pressure, but it will never make people feel energetic overnight

3. Chili pepper aphrodisiac

Many people in India and South America believe that chili peppers look like male genitals and taste pungent, just like fiery love. In fact, the substances contained in peppers only have antioxidant, metabolism-promoting, and pain-relieving effects, and have nothing to do with aphrodisiac.

4. Truffles aphrodisiac

The ancient Greeks and Romans believed in the aphrodisiac properties of truffles, a belief that has influenced many modern Europeans. However, according to James Trepp, a well-known American truffle research expert, the musky smell contained in truffles can only induce estrus in pigs, and there is no evidence that it is effective on humans.

5. Spices are refreshing and aphrodisiac

Many spices originating from Asia are believed to arouse sexual desire. However, Dr. Alan Jose of the Chicago Aroma and Flavor Therapy Research Foundation pointed out that measurements showed that the degree of congestion in the penis and vagina did not change much after using spices.